BDBM447470 US10689357, Example 9

SMILES COc1ccc(cc1)-c1ccc(C(=O)N[C@]23C[C@@](C2)(C3)N=C=S)c(F)c1

InChI Key InChIKey=JPZUICWGCDIWSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 447470   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM447470(US10689357, Example 9)
Affinity DataIC50: 1.00E+3nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM447470(US10689357, Example 9)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed