BDBM447478 US10689357, Example 16

SMILES COc1ccc(cc1)-c1cc(on1)C(=O)N[C@H]1C[C@H](C1)N=C=S

InChI Key InChIKey=MLBCXBQODVOSFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 447478   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM447478(US10689357, Example 16)
Affinity DataIC50: 55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

US Patent
LigandPNGBDBM447478(US10689357, Example 16)
Affinity DataIC50: 92nMAssay Description:Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed