BDBM447927 US10689367, Example 255.0::US10689367, Example 256.0

SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1[C@@H](C)c1ncc(C)o1)c1ncc(Cl)cn1

InChI Key InChIKey=KMWXPZZSBCUYFG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 447927   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM447927(US10689367, Example 256.0 | US10689367, Example 25...)
Affinity DataEC50:  0.480nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM447927(US10689367, Example 256.0 | US10689367, Example 25...)
Affinity DataEC50:  7.5nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent