BDBM448081 US10689390, Compound 37::US11319326, Compound 37

SMILES CCNC(=O)CC1N=C(c2ccc(Cl)cc2)c2cc(F)ccc2-c2cn(C)c(=O)cc12

InChI Key InChIKey=SNWQIUCCTFTLIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448081   

TargetBromodomain-containing protein 4 [44-168](Homo sapiens (Human))
Jubilant Biosys

US Patent
LigandPNGBDBM448081(US10689390, Compound 37 | US11319326, Compound 37)
Affinity DataIC50:  4nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Jubilant Biosys

US Patent
LigandPNGBDBM448081(US10689390, Compound 37 | US11319326, Compound 37)
Affinity DataIC50:  4nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent