BDBM4481 6,7-dialkoxyquinoline deriv. 51::[4-(3-Bromophenylamino)-6,7-dimethoxyquinolin-3-yl]-methanol::{4-[(3-bromophenyl)amino]-6,7-dimethoxyquinolin-3-yl}methanol

SMILES COc1cc2ncc(CO)c(Nc3cccc(Br)c3)c2cc1OC

InChI Key InChIKey=NMNOCAWQEQWSTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4481   

TargetEpidermal growth factor receptor(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4481({4-[(3-bromophenyl)amino]-6,7-dimethoxyquinolin-3-...)
Affinity DataIC50: 1.02E+5nMAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed