BDBM448147 9-benzyl-4-ethyl-2,2- dimethyl-1-oxa-4,9- diazaspiro[5.6]dodecan-3- one::US10689398, Example 57

SMILES CCN1CC2(CCCN(Cc3ccccc3)CC2)OC(C)(C)C1=O

InChI Key InChIKey=XAIGANLZIFWZNU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448147   

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM448147(9-benzyl-4-ethyl-2,2- dimethyl-1-oxa-4,9- diazaspi...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent