BDBM448148 4-((4-ethyl-2,2-dimethyl-3- oxo-1-oxa-4,9- diazaspiro[5.6]dodecan-9- yl)methyl)benzonitrile::US10689398, Example 58

SMILES CCN1CC2(CCCN(Cc3ccc(cc3)C#N)CC2)OC(C)(C)C1=O

InChI Key InChIKey=DEKYJSOSCLPAOR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448148   

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM448148(4-((4-ethyl-2,2-dimethyl-3- oxo-1-oxa-4,9- diazasp...)
Affinity DataKi: >500nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent