BDBM448192 (R)-2,2-dimethyl-9-phenethyl-1-oxa-4,9-diazaspiro[5.6]dodecan-4-yl)(phenyl)methanone and (S)-(2,2-dimethyl-9-phenethyl-1-oxa-4,9-diazaspiro[5.6]dodecane-4-yl)(phenyl)methanone::US10689398, Example 94::US10689398, Example 95

SMILES CC1(C)CN(C[C@]2(CCCN(CCc3ccccc3)CC2)O1)C(=O)c1ccccc1

InChI Key InChIKey=AVYCAHLIVKLAHU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448192   

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 448192BDBM448192((R)-2,2-dimethyl-9-phenethyl-1-oxa-4,9-diazaspiro[...)
Affinity DataKi: <500nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 448192BDBM448192((R)-2,2-dimethyl-9-phenethyl-1-oxa-4,9-diazaspiro[...)
Affinity DataKi: <500nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent