BDBM448331 USRE48059, Compound of Example 91

SMILES Fc1cc2CCNC(=O)c2cc1OCCCCN1CCN(CC1)c1cccc2sccc12

InChI Key InChIKey=CMHYKJRULRYQDT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448331   

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM448331(USRE48059, Compound of Example 91)
Affinity DataKi:  1.40nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM448331(USRE48059, Compound of Example 91)
Affinity DataKi:  6.5nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent