BDBM448528 7-(isoquinolin-1-yl)-N-methyl-2,3-dihydrobenzo[f][1,4]oxazepine-4(5H)-carboxamide::US10696655, Example 1::US11168070, Example 1

SMILES CNC(=O)N1CCOc2ccc(cc2C1)-c1nccc2ccccc12

InChI Key InChIKey=DTVDVNBQAJTARO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448528   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448528BDBM448528(US10696655, Example 1 | 7-(isoquinolin-1-yl)-N-met...)
Affinity DataIC50: 187nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448528BDBM448528(US10696655, Example 1 | 7-(isoquinolin-1-yl)-N-met...)
Affinity DataIC50: 187nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent