BDBM448637 N,1-dimethyl-3-(3-(1-methyl-1H-pyrazol-4-yl)isoquinolin-8-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamide::US10696655, Example 103::US11168070, Example 103

SMILES CNC(=O)c1ccc2c(c1)n(-c1cccc3cc(-c4cnn(C)c4)ncc13)c(=O)n2C

InChI Key InChIKey=GGVLERMNKOMODQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448637   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448637BDBM448637(US10696655, Example 103 | N,1-dimethyl-3-(3-(1-met...)
Affinity DataIC50: 222nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448637BDBM448637(US10696655, Example 103 | N,1-dimethyl-3-(3-(1-met...)
Affinity DataIC50: 222nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent