BDBM448657 N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl)-5- (trifluoromethyl)-phenyl)-5-(pyridin-4-yl)furan-2- carboxamide::US10696661, Compound 15

SMILES Cc1ccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(o2)-c2ccncc2)C(F)(F)F)o1

InChI Key InChIKey=PVNFHDUJWZPDNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448657   

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448657(N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl...)
Affinity DataIC50: 21.4nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent