BDBM448667 5-(pyridin-4-yl)-N-(2-(4-(thiazol-4-ylmethyl)piperazin-1-yl)-5- (trifluoromethyl)phenyl)furan-2-carboxamide::US10696661, Compound 22

SMILES FC(F)(F)c1ccc(N2CCN(Cc3cscn3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1

InChI Key InChIKey=GXESAQKBZJNLLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448667   

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448667(5-(pyridin-4-yl)-N-(2-(4-(thiazol-4-ylmethyl)piper...)
Affinity DataIC50: 13.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent