BDBM448680 N-(5-chloro-2-(4-(furan-2-ylmethyl)piperazin-1- yl)phenyl)picolinamide::US10696661, Compound 29

SMILES Clc1ccc(N2CCN(Cc3ccco3)CC2)c(NC(=O)c2ccccn2)c1

InChI Key InChIKey=BSWZYRFLJUYLRH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448680   

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448680(N-(5-chloro-2-(4-(furan-2-ylmethyl)piperazin-1- yl...)
Affinity DataIC50: 27.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent