BDBM448722 N-(2-(4-(isoxazol-4-ylmethyl)piperazin-1-yl)-5-(trifluoro- methyl)phenyl)furan-2-carboxamide::US10696661, Compound 66

SMILES FC(F)(F)c1ccc(N2CCN(Cc3cnoc3)CC2)c(NC(=O)c2ccco2)c1

InChI Key InChIKey=JCUVMZDIXFVMTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448722   

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448722(N-(2-(4-(isoxazol-4-ylmethyl)piperazin-1-yl)-5-(tr...)
Affinity DataIC50: 33.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent