BDBM448795 (S)-2-(1-methyl-1H-indazole-7-::US10696672, Compound 28a::US11634418, Compound 28a

SMILES Cn1ncc2cccc(C(=O)N[C@@H](CCN3CC[C@@H](CCc4ccc5CCCNc5n4)C3)C(O)=O)c12

InChI Key InChIKey=CIFHVCOEJLSBIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448795   

TargetIntegrin alpha-V/beta-6(Human)
Pliant Therapeutics

US Patent
LigandPNGBDBM448795((S)-2-(1-methyl-1H-indazole-7- | US10696672, Compo...)
Affinity DataIC50: 50nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 ug/ml) in PBS (100 ul/well 25° C. overnight). The coating solution was remo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetIntegrin alpha-V/beta-6(Human)
Pliant Therapeutics

US Patent
LigandPNGBDBM448795((S)-2-(1-methyl-1H-indazole-7- | US10696672, Compo...)
Affinity DataIC50: 50nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 ug/ml) in PBS (100 ul/well 25° C., overnight). The coating solution was rem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent