BDBM449003 US10696689, Compound 2-1::US11186590, Compound 2-1::methyl 4-(4-aminopiperidin-1-yl)-3-(6-fluoro-4-methoxy-1H-1,3-benzodiazol-2-yl)-5-(3-fluoro-5-methylphenyl)pyridine-2-carboxylate

SMILES COC(=O)c1ncc(-c2cc(C)cc(F)c2)c(N2CCC(N)CC2)c1-c1nc2cc(F)cc(OC)c2[nH]1

InChI Key InChIKey=XPRFCBRXEPLAPJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449003   

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM449003(methyl 4-(4-aminopiperidin-1-yl)-3-(6-fluoro-4-met...)
Affinity DataEC50:  0.550nMAssay Description:On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM449003(methyl 4-(4-aminopiperidin-1-yl)-3-(6-fluoro-4-met...)
Affinity DataEC50:  0.550nMAssay Description:Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent