BDBM449052 US10702498, Compound 9::US11484525, Compound 9

SMILES O=C(Cc1cn2ccccc2n1)NCC1(CCC1)c1ccccc1

InChI Key InChIKey=HMPRPWUCQHBMPY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 449052   

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449052(US10702498, Compound 9 | US11484525, Compound 9)
Affinity DataKi:  1.36E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449052(US10702498, Compound 9 | US11484525, Compound 9)
Affinity DataKi:  1.36E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449052(US10702498, Compound 9 | US11484525, Compound 9)
Affinity DataKi: <5.00E+4nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449052(US10702498, Compound 9 | US11484525, Compound 9)
Affinity DataKi: <5.00E+4nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent