BDBM449066 Thieno[2,3-c]pyridine-2- carboxylic acid 4- ((1R,3R,5S)-3-amino-8- aza-bicyclo[3.2.1]octane- 8-sulfonyl)-benzylamide::US10696692, Example 44

SMILES N[C@@H]1C[C@@H]2CC[C@H](C1)N2S(=O)(=O)c1ccc(CNC(=O)c2cc3ccncc3s2)cc1

InChI Key InChIKey=AESMKIURUHZWJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449066   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449066(Thieno[2,3-c]pyridine-2- carboxylic acid 4- ((1R,3...)
Affinity DataIC50: 5.80nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2021
Entry Details
US Patent