BDBM449069 US10702498, Compound 10::US11484525, Compound 10

SMILES CN(Cc1nnc(C2CC2)n1C)C(=O)NC[C@@H](Cc1ccccc1)[NH+](C)C

InChI Key InChIKey=VCESHEBUSPDJCF-UHFFFAOYSA-O

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 449069   

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449069(US10702498, Compound 10 | US11484525, Compound 10)
Affinity DataKi:  4.75E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449069(US10702498, Compound 10 | US11484525, Compound 10)
Affinity DataKi:  4.75E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449069(US10702498, Compound 10 | US11484525, Compound 10)
Affinity DataKi: <5.00E+4nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM449069(US10702498, Compound 10 | US11484525, Compound 10)
Affinity DataKi: <5.00E+4nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent