BDBM449077 US10696692, Example 55::[1-(4-{[(lmodazo[1,2- a]pyridine-6-carbonyl)- amino]-methyl}- benzenesulfonyl)- piperidin-4-yl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)NC1CCN(CC1)S(=O)(=O)c1ccc(CNC(=O)c2ccc3nccn3c2)cc1

InChI Key InChIKey=YRVJDGLBXPMRNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449077   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449077([1-(4-{[(lmodazo[1,2- a]pyridine-6-carbonyl)- amin...)
Affinity DataIC50: 7.70nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2021
Entry Details
US Patent