BDBM449092 US10696692, Example 70::cis-Imidazo[1,2- a]pyridine-6-carboxylic acid 4-((3aR,6aS)-5,5- difluoro-hexahydro- cyclopenta[c]pyrrole-2- sulfonyl)-benzylamide

SMILES FC1(F)C[C@@H]2CN(C[C@@H]2C1)S(=O)(=O)c1ccc(CNC(=O)c2ccc3nccn3c2)cc1

InChI Key InChIKey=JLKSUDGDAKFLIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449092   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449092(cis-Imidazo[1,2- a]pyridine-6-carboxylic acid 4-((...)
Affinity DataIC50: 6.40nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2021
Entry Details
US Patent