BDBM449127 Imidazo[1,2-a]pyridine-6-carboxylic acid 4-[4-(2- dimethylamino-ethyl)- piperazine-1-sulfonyl]- benzylamide::US10696692, Example 105

SMILES CN(C)CCN1CCN(CC1)S(=O)(=O)c1ccc(CNC(=O)c2ccc3nccn3c2)cc1

InChI Key InChIKey=BLQFYBGAWSKIGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449127   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449127(US10696692, Example 105 | Imidazo[1,2-a]pyridine-6...)
Affinity DataIC50: 6.80nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent