BDBM449216 N-[[4-[(6-methyl-2,6- diazaspiro[3.4]octan-2- yl)sulfonyl]phenyl]methyl] furo[2,3-c]pyridine-2- carboxamide::US10696692, Example 197::US10696692, Example 290

SMILES CN1CCC2(CN(C2)S(=O)(=O)c2ccc(CNC(=O)c3cc4ccncc4o3)cc2)C1

InChI Key InChIKey=YKRIOUVUXOSQFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449216   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449216(US10696692, Example 197 | N-[[4-[(6-methyl-2,6- di...)
Affinity DataIC50: 2.83nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449216(US10696692, Example 197 | N-[[4-[(6-methyl-2,6- di...)
Affinity DataIC50: 2.83nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent