BDBM449238 N-[[4-(1-oxa-7- azaspiro[4.4]nonan-7- ylsulfonyl)phenyl]methyl] imidazo[1,2-a]pyridine-6- carboxamide::US10696692, Example 219

SMILES O=C(NCc1ccc(cc1)S(=O)(=O)N1CCC2(CCCO2)C1)c1ccc2nccn2c1

InChI Key InChIKey=RPUIYKFBISCHCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449238   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449238(US10696692, Example 219 | N-[[4-(1-oxa-7- azaspiro...)
Affinity DataIC50: 8.45nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2021
Entry Details
US Patent