BDBM449286 N-[[4-[(6,6-difluoro-2- azaspiro[3.3]heptan-2- yl)sulfonyl]phenyl]methyl] imidazo[1,2-a]pyridine-6- carboxamide::US10696692, Example 270

SMILES FC1(F)CC2(CN(C2)S(=O)(=O)c2ccc(CNC(=O)c3ccc4nccn4c3)cc2)C1

InChI Key InChIKey=BIHKZCUKFZLKDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449286   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449286(US10696692, Example 270 | N-[[4-[(6,6-difluoro-2- ...)
Affinity DataIC50: 8.77nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2021
Entry Details
US Patent