BDBM449374 N-[[4-[[1-(2,2,2- tnfluoroethyl)-4- piperidyl]sulfinyl]phenyl] methyl]imidazo[1,2-a]pyridine- 6-carboxamide::US10696692, Example 364

SMILES FC(F)(F)CN1CCC(CC1)S(=O)c1ccc(CNC(=O)c2ccc3nccn3c2)cc1

InChI Key InChIKey=SNQXAVUOSPNPMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449374   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449374(N-[[4-[[1-(2,2,2- tnfluoroethyl)-4- piperidyl]sulf...)
Affinity DataIC50: 2.93nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2021
Entry Details
US Patent