BDBM449375 N-[[4-[(1-tetrahydropyran-4- yl-4- piperidyl)sulfinyl]phenyl] methyl]-1,3-dihydropyrrolo[3,4- c]pyridine-2-carboxamide::US10696692, Example 365

SMILES O=C(NCc1ccc(cc1)S(=O)C1CCN(CC1)C1CCOCC1)N1Cc2ccncc2C1

InChI Key InChIKey=QMPDVTMNWNLMKE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449375   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449375(N-[[4-[(1-tetrahydropyran-4- yl-4- piperidyl)sulfi...)
Affinity DataIC50: 2.02nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent