BDBM449386 N-[[4-[[1-(2,2,2- tnfluoroethyl)-4- piperidyl]sulfinyl]phenyl] methyl]-1,3-dihydropyrrolo[3,4- c]pyridine-2-carboxamide::US10696692, Example 376

SMILES FC(F)(F)CN1CCC(CC1)S(=O)c1ccc(CNC(=O)N2Cc3ccncc3C2)cc1

InChI Key InChIKey=KOEZAQIYWXRLQY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449386   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM449386(N-[[4-[[1-(2,2,2- tnfluoroethyl)-4- piperidyl]sulf...)
Affinity DataIC50: 5.82nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent