BDBM450192 9-{4-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-2-fluorobenzyl}-8-(5-fluoropyridin-3-yl)-2-methoxy-6-methyl-9H-purine::US10703755, Example 392::US10703755, Example 402

SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)[C@@H]3CN4CCC3CC4)c2n1

InChI Key InChIKey=BEYJDNZENUVEJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450192   

TargetToll-like receptor 7(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM450192(9-{4-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-2-fluorobe...)
Affinity DataIC50: 13nMAssay Description:As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter HEK293 cell), which is human embr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM450192(9-{4-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-2-fluorobe...)
Affinity DataIC50: 132nMAssay Description:As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter HEK293 cell), which is human embr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent