BDBM450256 US10676431, Example 20::US11117861, Example 20

SMILES CS(=O)(=O)Nc1ccccc1-c1ccc(cc1)N1CC[C@@H](NC(=O)Nc2ccc(nc2)C(F)(F)F)C1=O

InChI Key InChIKey=XPSJRGDAINTLGU-HXUWFJFHSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 450256   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450256(US10676431, Example 20 | US11117861, Example 20)
Affinity DataEC50:  24nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450256(US10676431, Example 20 | US11117861, Example 20)
Affinity DataEC50: >1.00E+4nMAssay Description:FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450256(US10676431, Example 20 | US11117861, Example 20)
Affinity DataEC50:  24nMAssay Description:FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450256(US10676431, Example 20 | US11117861, Example 20)
Affinity DataEC50: >1.00E+4nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent