BDBM450607 (2S,3R)-3-(2-(1-(2,5-bis(Trifluoromethyl)benzyl)piperidin-4-yl)-1,2,34-tetrahydroisoquinolin-7-yl)-3-cyclopropyl-2-methylpropanoic acid::US10676458, Example 1

SMILES C[C@@H]([C@@H](C1CC1)c1ccc2CCN(Cc2c1)C1CCN(Cc2cc(ccc2C(F)(F)F)C(F)(F)F)CC1)C(O)=O

InChI Key InChIKey=QBIQFQHQMXCELS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450607   

TargetFree fatty acid receptor 1(Human)
Merch Sharp & Dohne Corp. Rahway

US Patent
LigandPNGBDBM450607(US10676458, Example 1 | (2S,3R)-3-(2-(1-(2,5-bis(T...)
Affinity DataEC50:  611nMAssay Description:The assay was performed in 384-well format. HEK cells stably expressing human GPR40 were plated at 7500 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent