BDBM450609 Sodium (2S,3R)-methyl 3- ((S or R)-3-(1-(2,5- bis(trifluoro-methyl)- benzyl)-piperidin-4-yl)- 3,4-dihydro-2H-benzo[b]- [1,4]oxazin-6-yl)-3- cyclopropyl-2- methylpropanoate::US10676458, Example 3

SMILES C[C@@H](C(C1CC1)c1ccc2OCC(Nc2c1)C1CCN(Cc2cc(ccc2C(F)(F)F)C(F)(F)F)CC1)C([O-])=O

InChI Key InChIKey=LPHPCEZHCMLCBJ-UHFFFAOYSA-M

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450609   

TargetFree fatty acid receptor 1(Human)
Merch Sharp & Dohne Corp. Rahway

US Patent
LigandPNGBDBM450609(US10676458, Example 3 | Sodium (2S,3R)-methyl 3- (...)
Affinity DataEC50:  642nMAssay Description:The assay was performed in 384-well format. HEK cells stably expressing human GPR40 were plated at 7500 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
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Date in BDB:
3/11/2021
Entry Details
US Patent