BDBM450610 Sodium (2S,3S)-3-((R or S)-3-(1-(2,5-bis(trifluoromethyl)benzyl)piperidin-4-yl)-4-methyl-3,4-di-hydro-2H-benzo[b][1,4]oxazin-6-yl)-3-cyclopropyl-2-methylpropanoate::US10676458, Example 4::US10676458, Example 5

SMILES C[C@@H]([C@@H](C1CC1)c1ccc2OCC(C3CCN(Cc4cc(ccc4C(F)(F)F)C(F)(F)F)CC3)N(C)c2c1)C([O-])=O

InChI Key InChIKey=ZGZZSFIYDZCNLS-UHFFFAOYSA-M

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450610   

TargetFree fatty acid receptor 1(Human)
Merch Sharp & Dohne Corp. Rahway

US Patent
LigandPNGBDBM450610(US10676458, Example 4 | US10676458, Example 5 | So...)
Affinity DataEC50:  2.10E+3nMAssay Description:The assay was performed in 384-well format. HEK cells stably expressing human GPR40 were plated at 7500 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetFree fatty acid receptor 1(Human)
Merch Sharp & Dohne Corp. Rahway

US Patent
LigandPNGBDBM450610(US10676458, Example 4 | US10676458, Example 5 | So...)
Affinity DataEC50:  4.70E+3nMAssay Description:The assay was performed in 384-well format. HEK cells stably expressing human GPR40 were plated at 7500 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent