BDBM450625 US10676465, Example 2*

SMILES COCCn1c(CN2CCN(CC2)c2cccc3O[C@@H](Oc23)c2ccc(Cl)cc2F)nc2ccc(cc12)C(=O)OC

InChI Key InChIKey=WFMGZVFZKWRRJU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450625   

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450625(US10676465, Example 2*)
Affinity DataEC50:  6.60nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450625(US10676465, Example 2*)
Affinity DataEC50:  260nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent