BDBM450657 2-({4-[2-(4-cyanophenyl)-2-methyl-1,3- benzodioxol-4-yl]piperidin-1-yl}methyl)-1- (2-methoxyethyl)-1H-benzimidazole-6- carboxylic acid::US10676465, Example 34

SMILES COCCn1c(CN2CCC(CC2)c2cccc3OC(C)(Oc23)c2ccc(cc2)C#N)nc2ccc(cc12)C(O)=O

InChI Key InChIKey=BSFLMKRMDUEMTP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450657   

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450657(US10676465, Example 34 | 2-({4-[2-(4-cyanophenyl)-...)
Affinity DataEC50:  7.80nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450657(US10676465, Example 34 | 2-({4-[2-(4-cyanophenyl)-...)
Affinity DataEC50:  110nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent