BDBM450694 2-({4-[2-(4-chloro-2-fluorophenyl)-2- methyl-1,3-benzodioxol-4-yl]piperidin-1- yl}methyl)-1-{2- [methyl(methylsulfonyl)amino]ethyl}-1H- benzimidazole-6-carboxylic acid::US10676465, Example 71

SMILES CN(CCn1c(CN2CCC(CC2)c2cccc3OC(C)(Oc23)c2ccc(Cl)cc2F)nc2ccc(cc12)C(O)=O)S(C)(=O)=O

InChI Key InChIKey=JPDYSRPXQGWKCK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450694   

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450694(US10676465, Example 71 | 2-({4-[2-(4-chloro-2-fluo...)
Affinity DataEC50:  6.80nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450694(US10676465, Example 71 | 2-({4-[2-(4-chloro-2-fluo...)
Affinity DataEC50:  74nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent