BDBM450708 1-(2-methoxyethyl)-2-({4-[2-methyl-2-(4- methylphenyl)-1,3-benzodioxol-4- yl]piperidin-1-yl}methyl)-1H- benzimidazole-6-carboxylic acid, formate salt::US10676465, Example 84

SMILES COCCn1c(CN2CCC(CC2)c2cccc3OC(C)(Oc23)c2ccc(C)cc2)nc2ccc(cc12)C(O)=O

InChI Key InChIKey=HHFUKSUWDLTSEI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450708   

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450708(US10676465, Example 84 | 1-(2-methoxyethyl)-2-({4-...)
Affinity DataEC50:  9.10nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450708(US10676465, Example 84 | 1-(2-methoxyethyl)-2-({4-...)
Affinity DataEC50:  100nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent