BDBM450724 2-({4-[(2S)-2-(4-chloro-2-fluorophenyl)-2- methyl-1,3-benzodioxol-4-yl]piperidin-1- yl}methyl)-7-fluoro-1[(2S)-oxetan-2- ylmethyl]-1H-benzimidazole-6-carboxylic acid, hemicitrate salt [from P3]::US10676465, Example 100

SMILES C[C@@]1(Oc2cccc(C3CCN(Cc4nc5ccc(C(O)=O)c(F)c5n4C[C@@H]4CCO4)CC3)c2O1)c1ccc(Cl)cc1F

InChI Key InChIKey=WHJPBEHUCSCVDL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450724   

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450724(US10676465, Example 100 | 2-({4-[(2S)-2-(4-chloro-...)
Affinity DataEC50:  7.60nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent