BDBM450729 US10676467, Compound 8b::US10676467, Compound TZ 48 25

SMILES OCc1ccc(cc1)-c1noc(n1)-c1ccc(OCCF)c(c1)C#N

InChI Key InChIKey=UNJXVOCWXAELHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450729   

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandPNGBDBM450729(US10676467, Compound 8b | US10676467, Compound TZ ...)
Affinity DataIC50: 15.4nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandPNGBDBM450729(US10676467, Compound 8b | US10676467, Compound TZ ...)
Affinity DataIC50: 15.4nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent