BDBM450765 US10676467, Compound TZ 43 73

SMILES NS(=O)(=O)c1ccc(cc1)-c1noc(n1)-c1ccc(OCCF)c(c1)C(F)(F)F

InChI Key InChIKey=LLKJSLXZRHRFBP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 450765   

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandPNGBDBM450765(US10676467, Compound TZ 43 73)
Affinity DataIC50: 13.2nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 2(Human)
Washington University

US Patent
LigandPNGBDBM450765(US10676467, Compound TZ 43 73)
Affinity DataIC50: 1.00E+3nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Washington University

US Patent
LigandPNGBDBM450765(US10676467, Compound TZ 43 73)
Affinity DataIC50: 1.00E+3nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent