BDBM450784 US10676467, Compound TZ 50 17

SMILES CN1CCc2c([nH]c3ccc(OCc4ccc(C5CCCC5)c(c4)C(F)(F)F)cc23)C1CC(O)=O

InChI Key InChIKey=WMKJKPPTJLNUSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 450784   

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandPNGBDBM450784(US10676467, Compound TZ 50 17)
Affinity DataIC50: 7.30nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 2(Human)
Washington University

US Patent
LigandPNGBDBM450784(US10676467, Compound TZ 50 17)
Affinity DataIC50: 1.00E+3nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Washington University

US Patent
LigandPNGBDBM450784(US10676467, Compound TZ 50 17)
Affinity DataIC50: 1.00E+3nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent