BDBM450880 US10676469, Compound 151::US11124504, Cpd. No. 151

SMILES CCc1cc(F)c2nc(N3CCC(CC3)N[C@H]3CCCOC3)c(-c3noc(C)n3)c(C)c2c1

InChI Key InChIKey=NFDDRYZYINAUHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450880   

TargetKappa-type opioid receptor(Human)
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450880(US10676469, Compound 151 | US11124504, Cpd. No. 15...)
Affinity DataIC50: 5.5nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450880(US10676469, Compound 151 | US11124504, Cpd. No. 15...)
Affinity DataIC50: 1.00E+3nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent