BDBM451397 US10709718, Compound 22

SMILES CCP(O)(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)C1=Nc2c(N)ncnc2OC1(C)C

InChI Key InChIKey=CUGJHKWWFGVRPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 451397   

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451397(US10709718, Compound 22)
Affinity DataIC50: 55nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent