BDBM451399 US10709718, Compound 24

SMILES [O-]P1(=O)OCCC(O1)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccccc2)cc1

InChI Key InChIKey=ZWJAGDQXHVCRJX-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 451399   

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451399(US10709718, Compound 24)
Affinity DataIC50: 550nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent