BDBM451697 US10710967, Example 292

SMILES CC#Cc1ncc(s1)-c1cc(=O)[nH]c(n1)-c1c(Cl)ccc(CNC(=O)C(C)C)c1F

InChI Key InChIKey=LFOILIYVCVTOIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 451697   

TargetProstaglandin E synthase(Human)
Aska Pharmaceutical

US Patent
LigandPNGBDBM451697(US10710967, Example 292)
Affinity DataIC50: 1nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent