BDBM451754 7-(2-amino-5- (benzo[d]thiazol-7-yl)pyridin- 3-yl)quinazolin-4(3H)-one::US10710978, Compound I-64

SMILES Nc1ncc(cc1-c1ccc2c(c1)nc[nH]c2=O)-c1cccc2ncsc12

InChI Key InChIKey=UVSMTBSUZIWXNK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 451754   

TargetSerine/threonine-protein kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM451754(7-(2-amino-5- (benzo[d]thiazol-7-yl)pyridin- 3-yl)...)
Affinity DataIC50: 120nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 3(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM451754(7-(2-amino-5- (benzo[d]thiazol-7-yl)pyridin- 3-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 26(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM451754(7-(2-amino-5- (benzo[d]thiazol-7-yl)pyridin- 3-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent