BDBM452542 3-((3-((3R,5R)-5-(4- fluorophenyl)tetrahydro- furan-3-yl)-1,2,4- oxadiazol-5-yl)methyl)- 5-methylpyrido[2,3- d]pyrimidin-4(3H)-one::US10710994, Example 20

SMILES Cc1ccnc2ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc(F)cc3)c(=O)c12

InChI Key InChIKey=MANPXGYRIORUOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452542   

LigandPNGBDBM452542(3-((3-((3R,5R)-5-(4- fluorophenyl)tetrahydro- fura...)
Affinity DataIC50: 3.60nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandPNGBDBM452542(3-((3-((3R,5R)-5-(4- fluorophenyl)tetrahydro- fura...)
Affinity DataIC50: 7.05nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent