BDBM452551 1-((3-((3R,5R)-5-(4- bromophenyl)tetra- hydrofuran-3-yl)- 1,2,4-oxadiazol-5-yl) methyl)-7-methyl-1,7- dihydro-6H-purin- 6-one::US10710994, Example 29

SMILES Cn1cnc2ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc(Br)cc3)c(=O)c12

InChI Key InChIKey=YVYCTLLAVRNGEF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452551   

LigandPNGBDBM452551(1-((3-((3R,5R)-5-(4- bromophenyl)tetra- hydrofuran...)
Affinity DataIC50: 1.80nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandPNGBDBM452551(1-((3-((3R,5R)-5-(4- bromophenyl)tetra- hydrofuran...)
Affinity DataIC50: 7.83nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent