BDBM452611 2-amino-3-((3-((3R,5R)- 5-(4-fluorophenyl) tetrahydrofuran-3-yl)-1,2,4- oxadiazol-5-yl)methyl) pyrido[2,3-d]pyrimidin- 4(3H)-one::US10710994, Example 89

SMILES Nc1nc2ncccc2c(=O)n1Cc1nc(no1)[C@@H]1CO[C@H](C1)c1ccc(F)cc1

InChI Key InChIKey=VSNLJSZHSKJANJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452611   

LigandPNGBDBM452611(2-amino-3-((3-((3R,5R)- 5-(4-fluorophenyl) tetrahy...)
Affinity DataIC50: 2.90nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent

LigandPNGBDBM452611(2-amino-3-((3-((3R,5R)- 5-(4-fluorophenyl) tetrahy...)
Affinity DataIC50: 18.7nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent